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Severe community acquired pneumonia (SCAP) has raised substantial concern due to high morbidity and mortality. SCAP is usually associated with multiple organ dysfunction syndrome (MODS) and sepsis. It is suggested that organ function and coagulation/fibrinolysis improvement, organ injury reduction and organ repair facilitation are highly required besides microbiology detection and optimization of antibiotics strategy on treatment of SCAP. Neutralization antibody, steroid, immunmodulatory therapy, and Chinese medicine etc. contribute to organ function improvement from different perspective. The unique profile of multiple target and personalized therapy of Chinese medicine may become a promising new option for SCAP and MODS. The combination of Western and Chinese Medicine shed new light on SCAP treatment.
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Objective@#To investigate the knowledge, attitude and practice(KAP) of salt and health among primary school students in Jinan, and to provide scientific evidence for targeted interventions.@*Methods@#1 293 primary school students of grade 4 in Jinan were randomly selected by cluster sampling method, and a self-designed questionnire on "salt and health" was applied among them.@*Results@#Among grade 4 students in Jinan, 35.73% were aware the diagnostic criteria of hypertension in adults, 67.67% were aware that eating less salt help lowering blood pressure. The proportion of students who knew the recommended daily intake of salt for adults, children aged 1-6 years and for children aged 7-13 years was 55.68%, 53.21% and 50.62%, respectively. The proportion of students who favor lower intake of salt(70.84%), actively choose low-salt food(65.89%), received publicity or education on low-salt diet(72.85%), pay attention to the salt/sodium content when purchasing packaged food(73.01%), believe that packaged food should be labelled with salt/sodium content(84.45%), and heard of low-sodium salt (alternative salt)(57.77%).The boys and girls were found no statistical significance in the differences of their attitude toward controlling salt, skills and behaviors(P<0.05),with 68.05% of boys and 73.91% of girls agreed, 13.76% of boys and 9.24% of girls reported no attention paid. There was no significant difference in other salt control attitudes, skills and behaviors between boys and girls(P>0.05).@*Conclusion@#A series of interventions taken by Shandong Ministry of Health Action on Salt Reduction and Hypertension (SMASH) within schools show positive effects. However, gaps in salt taste and salt intake among primary school students still exist, suggesting health education should be further strengthened in respect of daily salt intake recommendation, salt intake attitude and behaviors, especially for boys.
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Objectives To investigate the imaging ability of magnetic sensitive weighted imaging (SWI) scans with 2.0 mm and 1.0 mm slice thickness on intracerebral veins and branches.Methods 47 healthy volunteers were recruited,including 20 males and 27 females,aged 21-45 (30.1 ± 12.93).Two SWI sequences with thickness of 2.0 mm and 1.0 mm were performed in all healthy volunteers.After reconstructed by minimal intensity projection (MIP),the display rate and diameter of intracerebral veins and branches were counted by two doctors.McNemar test and paired t-test were used for statistical analysis.Results (1) The display rates of bilateral internal cerebral veins,papular veins and left ventricular veins were 100％ in both scanning schemes,while the display rates of left and right septal veins,anterior caudate nucleus veins and right ventricular veins on SWI sequence images with 2.0 mm thickness were 90.0％ (left),91.0％ (right) and 87.2％ (right),91.5％,respectively.The display rates on SWI sequence images with 1.0 mm thickness were 97.9％ (left),94.0％ (right),97.9％ (left),95.7％ (right) and 95.7％ respectively.(2) There were significant differences in the diameter of bilateral septum pellucidum veins and bilateral anterior caudate nucleus veins between the two scanning schemes (P ＜ 0.05).While there was no significant difference in the diameter of bilateral internal cerebral veins,bilateral papular veins and bilateral intraventricular veins (P ＞0.05).(3) The displaying rate of veins with diameter ＞0.9 mm was 100％ for both scanning schemes,while the displaying rate of veins with diameter ranging from 0.6-0.9 mm (including 0.6 mm and 0.9 mm) in the two scanning schemes had significant difference (P ＜ 0.05).Conclusions SWI sequence can clearly show the anatomical shape of intracerebral veins and branches.In contrast to SWI of the scan slices thickness of 2.0 mm,the SWI of scan slices thickness of 1.0 mm showed more efficiency in display thinner brain venous.Therefore,using SWI sequence scanning scheme with 1.0 mm slice thickness will be more conducive to observe and study intracerebral veins and branches.
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Objective To explore the clinical value of CEUS guided biopsy of lymphoma in anterior mediastinum.Methods The data of 36 patients with lymphoma of anterior mediastinum underwent biopsy guided by CEUS and 36 patients by conventional ultrasound retrospectively.The successful rate of biopsy and rate of complication occurence were compared between the CEUS group and conventional ultrasound group.Results The successful rate of biopsy in CEUS group was 100％ (36/36),including 26 non-Hodgkin's lymphoma (NHL),10 Hodgkin's lymphoma (HL).The total times of puncture were 60 in 36 patients.The rate of complication occurrence was 11.11 ％ (4/36).The successful rate in conventional ultrasound group was 88.89％ (32/36),including 22 NHL,14 HL.The times of puncture were 91 in 36 patients.The rate of complication occurrence was 41.67％ (15/36).There were significant differences in successful rate and the rate of complication occurrence between two groups (x2 =4.235,8.651,P=0.040,0.003).Conclusion CEUS can reflect the microcirculation of lymphomas in anterior mediastinum,and can guide targeted biopsy.It can improve the successful rate of biopsy and reduce the complications.
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Objective Toinvestigatetheeffectofwhetherposteriorcommunicatingartery(PCoA) patent or not on hemodynamics of extracranial internal carotid artery (EICA)in patients with moyamoya disease.Methods Atotalof103consecutivepatientswithmoyamoyadisease(unilaterallesion) detected by transcranial color Doppler ultrasonography (TCD)and Color Doppler flow imagining (CDFI), and confirmed by digital subtraction angiography (DSA)from August 2008 to April 2014 were enrolled. According to the patency of PCoA showed by DSA,the patients were divided into either a PCoA non-patent group (n=83)and a PCoA patent group (n=20). Eighty healthy subjects screened by TCD and CDFI in the same period were used as a control group. CDFI and TCD were used to detect the peak systolic velocity (PSV),end diastolic velocity (EDV),vascular resistance index (RI)and/or pulsatility index (PI)of EICA,and posterior cerebral artery (PCA)in subjects of both groups. Results (1 )There were significant differences in PSV,EDV and RI among the three groups (F=5. 76,12. 24,and 8. 10,respectively;all P<0. 05). The PSV of vascular EICA (42 ± 15 cm/s)and EDV (14 ± 7 cm/s)on the lesion sites in patients of the PCoA non-patent group were all lower than those in the control group (92 ± 24 and 38 ± 11 cm/s). The differences were statistically significant (all P<0. 05). The PSV of vascular EICA on the lesion sites in patients of the PCoA patent group was lower than that of the control group (P<0. 05),but EDV was higher than the control group (P<0. 05). (2)Compared with the control group,the RI value was increased in the PCoA non-patent group (P<0. 01)and that was decreased in the PCoA patent group (P<0. 01). (3)PSV and EDV of PCA in the moyamoya disease group were higher than those of the control group (P<0.05),andthePIvaluewaslowerthanthatofthecontrolgroup(P<0.01).Conclusion Whether PCoA patent or not in patients with moyamoya disease have different influences on hemodynamic parameters of EICA. PSV and EDV of the patients with PCoA non-patent are lower than those of the healthy subjects and their RI values are increased. EICA of the patent group is lower than PSV and RI of the control group, and their EDV is increased.
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MicroRNAs (miRNAs)are small,non-coding RNAs that regulate the translation of specific protein coding genes. Recent studies have revealed the role of miRNAs in a variety of basic biological and pathological processes.Previous studies have suggested miRNAs can be servered as a new tumor biomarker in the early diagnosis,treatment and assessment of prog-nosis of CRC,which also can be servered as the treatment target in vivo of CRC patients.This paper reviews the expression and targets of miRNAs,its mechanism of the development and prospect in clinical application in CRC.
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Objective To investigate the clinical value and characteristics of color Doppler ultrasound in the diagnosis of fetal ductus arteriosus narrow.Methods 22 pregnant women were screened by ultrasound in the hospital (the disease group),In the same period,50 cases of fetus in pregnant women were selected as control group,The arterial catheter inside diameter,systolic and diastolic velocity flow were compared,and different facets of the ductus arteriosus in ultrasonography were observed.Results The ductus arteriosus diameter of disease group gestational age (28-36 weeks) and gestational age (＞ 36 weeks) were (2.25 ± 0.68) mm and (4.29 ± 0.14) mm,which were significantly lower than those in the control group(t =3.01,2.98,all P ＜ 0.05).The systolic flow rate of disease group gestational age (28-36 weeks) was (0.39 ± 0.20) m/s,which was significantly higher than (0.32 ± 0.31) m/s in the control group (t =2.96,P ＜ 0.05).The systolic and diastolic flow velocity of disease group gestational age (＞ 36 weeks) were (0.42 ± 0.17) m/s,and (0.24 ± 0.08) m/s,which were significantly higher than those of the control group (t =2.91,3.04,all P ＜ 0.05).The color Doppler ultrasound of fetal ductus arteriosus narrow showed arterial catheter lumen thinner,blood flow velocity was significantly faster,including five cases of arterial stenosis showed right atrium,right ventricle; 3 cases showed the right atrium and right ventricle increased,with severe tricuspid regurgitation.Conclusion Color Doppler ultrasound can identify fetal ductus arteriosus braid and can objectively and comprehensively assess it.It has important diagnostic value for fetal ductus arteriosus stenosis.
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OBJECTIVE@#To study surgical techniques and clinical applications of the intranasal endoscopic combined approach in maxillary sinus benign lesions surgery.@*METHOD@#A retrospective clinical analysis of 27 patients "whose unilateral maxillary sinus benign lesions operated by the intranasal endoscopic middle meatus with inferior meatus tears recess approach surgical treatment was studied.@*RESULT@#Benign lesions were confirmed by pathology in all patients before and after surgery as to rule out malignancy. All patients had been followed up for 12 to 24 months. Twenty-seven cases resulted in normal luminal epithelium and inferior turbinate shape after surgery. Only one case of papilloma relapsed 2 months after operation. So far, the papilloma has not recurred after the second surgery. There were no epiphora in all cases.@*CONCLUSION@#Endonasal endoscopic expand anterior tears recess approach have great and clear view. This approach made us accurately, mini-invade and completely remove the maxillary sinus benign lesions. It is a physiological and functional surgery and has great advantage in the nasal cavity disease treatment.
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Endoscopy , Methods , Lacrimal Apparatus , General Surgery , Maxillary Sinus , Nasal Surgical Procedures , Methods , Nose , General Surgery , Paranasal Sinus Diseases , General Surgery , Retrospective StudiesABSTRACT
Objective To study the clinical value of vascular ultrasound examination in detection of carotid artery disease. Methods 53 cases of ischemic cerebrovascular disease who served as experimental group,tested 387 vessels; and used the same period 55 cases of healthy persons as control group, tested 394 blood vessels. Comparison of two blood flow parameters between groups with differences in plaque detection. Results The results of vascular ultrasound examination could detect the visual display and quantitative carotid artery lesions in the experimental group a significant thickening of carotid artery IMT,carotid artery plaque prevalence was significantly higher than control group (P ＜0.01). Conclusion Vascular ultrasound examination was an effective screening method to detect ischemic cerebrovascular disease.
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Professor CHAO En-xiang thinks that several rules should be obeyed when we treat gangrenous appendicitis complication with paralytic ileus and ARDS.Firstly,we should adhere to the TCM characteristics of the holistic concept and treatment based on syndrome of differentiation.Secondly,we should formulate therapeutic method according to major pathogenesis.Thirdly,we should use drugs flexibly according to the patient's specific situation.Professor CHAO En-xiang considered it was the syndrome of dysfunctional activity of qi,fu qi being obstructed,dysfunction of middle-jiao in transportation.The therapeutical principle was regulating qi activity,dredging intestines and relieving distention.Nasal feeding with Dachengqi decoction adding Agastache rugosa,Tatarian Aster,paste umbilicus with mud of shallot stalk,fresh ginger,fennel and enema with Radix Aucklandiae.
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This paper studies the mental health methods of Confucian doctrine,Taoism,Buddhism school and Legalist school from its main characteristic,theory basis,basic request and specific implementation procedure,in order to carry forward Chinese traditional culture and inaugurate the psychic health education,consummating solicitude and psychological consultation.